General description
Native protein C from human plasma. Sold as a zymogen. Markedly prolongs kaolin-cephalin clotting time of normal plasma. Activated by α-thrombin to serine protease-activated protein C. In its active form, it is a potent anticoagulant that acts through selective inactivation of Factors Va and VIIIa.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Esmon, N.L., et al. 1999. Haematologica 84, 363.
Packaging
100 µg in Plastic ampoule
Physical form
In 100 mM NaCl, 20 mM Tris-HCl, 1 mM benzamidine, pH 7.4.
Preparation Note
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitution
Following initial thaw, aliquot and freeze (-70°C).
Warning
Toxicity: Standard Handling (A)
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